Peptide Database

Peptide NameUnnamed

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Reproductive neuropeptide

Regulatory peptide ▸ Biological modulation

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length68 amino acids

Chemical FormulaC334H532N102O106S2

DescriptionStandard

        QHWSYGLRPGGKRNAENVIDSFQEMAKEVARLAEPQRFECTAHQPRSPLRDLKGALESLIEEETGQKT
    

Molecular Weight7736.55 Da

Isoelectric Point (pI)6.12

Net Charge (pH 7.0)-1.05

Net Charge (pH 7.4) -1.40

Charge Density (pH 7.0) -0.0155

GRAVY Index-0.98

Hydrophobic Moment 0.76

Boman Index-0.22

Instability Index75.54

Aliphatic Index 63.24

Aromaticity 0.0588

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3400.26

LogP -37.35

H-bond Donors 117.0

H-bond Acceptors 109.0

Rotatable Bonds 262.0

Heavy Atoms 544.0

Ring Count 11.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0079815 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0200585 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyProgonadoliberin

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator Receptor modulation

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0397544 VERIFIED: NO

Provenance & Taxonomy

OrganismSus scrofa [Animal]

FamilyGnRH

Tax ID9823

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

Other ModsGly10 Amidation

Bio-Activity Profile

Function

Hormone Reproductive neuropeptide