Peptide Database

Peptide NameNeuropeptide S precursor

Function Ontology

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Immunology ▸ Immune modulation ▸ Immunomodulatory activity

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological modulation

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC331H551N99O90S4

DescriptionStandard

        HPISSSKVPGKSDYFVILLNSCPTRMDRRVGLDFLKPILEKTLMKRSFRNGVGTGMKKTSFRRAKS
    

Molecular Weight7485.79 Da

Isoelectric Point (pI)11.06

Net Charge (pH 7.0)10.83

Net Charge (pH 7.4) 10.55

Charge Density (pH 7.0) 0.1642

GRAVY Index-0.48

Hydrophobic Moment 0.68

Boman Index-0.17

Instability Index47.98

Aliphatic Index 72.27

Aromaticity 0.0758

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3088.17

LogP -32.40

H-bond Donors 113.0

H-bond Acceptors 106.0

Rotatable Bonds 256.0

Heavy Atoms 524.0

Ring Count 10.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0140181 VERIFIED: NO

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyNeuropeptide S precursor

Tax ID9913

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide Neuromodulator Receptor modulation Immunomodulatory ACE inhibitory

Half-LifeMammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour