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MYP_109832
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Basic Information
Brevinin-1TEa (Frogs, amphibians, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
24 amino acids
C119H198N28O27S2
Standard
Sequence
FFGPLIKIATGVLPNLICKALGKC
Physicochemical Analysis
2517.15 Da
9.39
2.74
2.50
0.1141
1.12
0.52
0.42
3.46
134.17
0.0833
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
856.42
-3.54
30.0
32.0
81.0
176.0
4.0
24.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0218708 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 45.8%, E 0.0%, T 33.3%, C 20.8% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial
PaperYADAMP: yet another database of antimicrobial peptides PMID22325123 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22325123/
RECORD: Rec_0265720 VERIFIED: YES
Provenance & Taxonomy
Hylarana temporalis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus (ATCC25923)
150 μg/mL
MIC
PMID21412958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21412958/
RECORD: Rec_0276498 VERIFIED: YES
Provenance & Taxonomy
Hylarana temporalis [Animal]
Brevinin
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Bacillus cereus (NCLM 2156)
100 μg/mL
MIC
PMID21412958 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21412958/
RECORD: Rec_0372790 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperPatent WO 2019/077634 A2 Evidence URLhttps://patents.google.com/patent/WO2019077634A2/en PatentWO 2019/077634 A2
RECORD: Rec_0385736 VERIFIED: YES
Provenance & Taxonomy
Hylarana temporalis [Animal]; Indosylvirana temporalis [Animal]
Brevinin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Hemolytic
Haemolytic activity against human red blood cells
95 μg/mL
MIC
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