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MYP_109825
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Basic Information
Insulin-releasing-peptide
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Hormonal / Endocrine ▸ Hormone peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
28 amino acids
C133H225N37O39S
Standard
Sequence
ALWKDILKNVGKAAGKAVLNTVTDMVNQ
Physicochemical Analysis
2998.50 Da
9.53
1.79
1.60
0.0641
0.07
0.73
0.10
4.09
111.43
0.0357
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1256.31
-11.77
42.0
42.0
103.0
210.0
2.0
31.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0042100 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa tarsius [Animal]
Dermaseptin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Candida albicans
Evidence URLhttps://camp.bicnirrh.res.in/seqDisp.php?id=CAMPSQ4508
RECORD: Rec_0055677 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 27853
11.6 μM
MIC
PMID9614066 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9614066/
RECORD: Rec_0057243 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa CIP A22
4.6 μM
MIC
PMID9614066 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9614066/
RECORD: Rec_0067516 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
8393
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
Bio-Activity Profile
Antimicrobial
Staphylococcus aureus ATCC 25923
3.0 μM
MIC
PaperStructure, synthesis, and molecular cloning of dermaseptins B, a family of skin peptide antibiotics.
RECORD: Rec_0076863 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
8393
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
Bio-Activity Profile
Antimicrobial
Escherichia coli ATCC 25922
5.0 μM
MIC
PaperStructure, synthesis, and molecular cloning of dermaseptins B, a family of skin peptide antibiotics.
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