‹ ›
MYP_109825
← PREVIOUS NEXT → BACK
Basic Information
Insulin-releasing-peptide
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Hormonal / Endocrine ▸ Hormone peptide
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
28 amino acids
C133H225N37O39S
Standard
Sequence
ALWKDILKNVGKAAGKAVLNTVTDMVNQ
Physicochemical Analysis
2998.50 Da
9.53
1.79
1.60
0.0641
0.07
0.73
0.10
4.09
111.43
0.0357
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1256.31
-11.77
42.0
42.0
103.0
210.0
2.0
31.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0002637 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa trinitatis [Animal]
Insulin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Escherichia coli
5.0 μM
MIC
PaperS. Charpentier et al. / The Journal of Biological Chemistry 273 (1998) 14690-14697. Structure, synthesis, and molecular cloning of dermaseptins B, a family of skin peptide antibiotics
RECORD: Rec_0011947 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
8393
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
Bio-Activity Profile
Antimicrobial
Escherichia coli 54127
2.3 μM
MIC
PaperStructure, synthesis, and molecular cloning of dermaseptins B, a family of skin peptide antibiotics.
RECORD: Rec_0027232 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Insulin releasing
PaperM. Amiche et al. / Peptides 29 (2008) 2074-2082. A consistent nomenclature of antimicrobial peptides isolated from frogs of the subfamily Phyllomedusinae Evidence URLhttps://www.uniprot.org/uniprotkb/P81486/entry
RECORD: Rec_0036267 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PMID9614066 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9614066/
RECORD: Rec_0037398 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa bicolor [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli 54127
2.3 μM
MIC
PMID9614066 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/9614066/
1 2 3 ... 9 NEXT LAST
Showing 5 records on this page · Page 1 of 9