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MYP_109764
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
38 amino acids
C189H337N67O50
Standard
Sequence
GRLRNLIEKAGQNIRGKIQGIGRRIKDILKNLQPRPQV
Physicochemical Analysis
4348.12 Da
12.00
7.76
7.55
0.2042
-0.82
0.88
-0.31
67.73
112.89
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1974.15
-20.23
68.0
58.0
157.0
306.0
2.0
44.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0096834 VERIFIED: NO
Provenance & Taxonomy
Mammalia [Animal]
Cathelicidin
40674
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0116422 VERIFIED: YES
Provenance & Taxonomy
Ailuropoda melanoleuca [Animal]
Cathelicidin
9646
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Pseudomonas aeruginosa 1411
6.5 μg/mL
MIC
PMID22101189 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22101189/
RECORD: Rec_0122619 VERIFIED: YES
Provenance & Taxonomy
Ailuropoda melanoleuca [Animal]
Cathelicidin
9646
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida albicans ATCC 2002
6.5 μg/mL
MIC
PMID22101189 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22101189/
RECORD: Rec_0158339 VERIFIED: YES
Provenance & Taxonomy
Ailuropoda melanoleuca [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0158743 VERIFIED: YES
Provenance & Taxonomy
Ailuropoda melanoleuca [Animal]
Cathelicidin
9646
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Acinetobacter calcoaceticus
3.28 μg/mL
MIC
PMID22101189 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22101189/
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