MYP_109758
Basic Information
Brevilaterin B
Anticancer
Anticancer Cytotoxic anticancer activity Cytotoxic
Antimicrobial
Toxicity / Safety Blood cell toxicity Hemolysis Hemolytic
Toxicity / Safety Cytotoxicity Cytotoxic
Venom / Toxin General toxin Cytotoxic
not Standard
14 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XXMXIVVKVLKYLX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0309068 VERIFIED: YES
Provenance & Taxonomy
Brevibacillus laterosporus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
X(1)=Hmp=2-hydroxy-3-methylpentanoic acid; X(2)=Aba=2-amino-2-butenoic acid; X(4)=Ornithine; X(14)=valinol
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7
4.94±0.28 μg/mL
IC50
RECORD: Rec_0310815 VERIFIED: YES
Provenance & Taxonomy
Brevibacillus laterosporus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
X(1)=Hmp=2-hydroxy-3-methylpentanoic acid; X(2)=Aba=2-amino-2-butenoic acid; X(4)=Ornithine; X(14)=valinol
Bio-Activity Profile
Antimicrobial Anticancer
EC109
2.13±0.23 μg/mL
IC50
RECORD: Rec_0318677 VERIFIED: YES
Provenance & Taxonomy
Brevibacillus laterosporus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
X(1)=Hmp=2-hydroxy-3-methylpentanoic acid; X(2)=Aba=2-amino-2-butenoic acid; X(4)=Ornithine; X(14)=valinol
Bio-Activity Profile
Antimicrobial Anticancer
MDA-MB-231
4.16±0.27 μg/mL
IC50
RECORD: Rec_0354482 VERIFIED: YES
Provenance & Taxonomy
Brevibacillus laterosporus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
X(1)=Hmp=2-hydroxy-3-methylpentanoic acid; X(2)=Aba=2-amino-2-butenoic acid; X(4)=Ornithine; X(14)=valinol
Bio-Activity Profile
Antimicrobial Anticancer
HT-29
1.4±0.09 μg/mL
IC50
RECORD: Rec_0361568 VERIFIED: YES
Provenance & Taxonomy
Brevibacillus laterosporus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
X(1)=Hmp=2-hydroxy-3-methylpentanoic acid; X(2)=Aba=2-amino-2-butenoic acid; X(4)=Ornithine; X(14)=valinol
Bio-Activity Profile
Antimicrobial Anticancer
A-375
4.16±0.15 μg/mL
IC50
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