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MYP_109758
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Basic Information
Brevilaterin B
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
14 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
XXMXIVVKVLKYLX
Physicochemical Analysis
0.00 Da
0.00
0.00
0.00
0.00
0.00
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0196832 VERIFIED: YES
Provenance & Taxonomy
Brevibacillus laterosporus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
X(1)=Hmp=2-hydroxy-3-methylpentanoic acid; X(2)=Aba=2-amino-2-butenoic acid; X(4)=Ornithine; X(14)=valinol
Bio-Activity Profile
Antimicrobial Anticancer
SK-OV-3
4.26±0.25 μg/mL
IC50
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP32372
RECORD: Rec_0205720 VERIFIED: YES
Provenance & Taxonomy
Brevibacillus laterosporus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
X(1)=Hmp=2-hydroxy-3-methylpentanoic acid; X(2)=Aba=2-amino-2-butenoic acid; X(4)=Ornithine; X(14)=valinol
Bio-Activity Profile
Antimicrobial Anticancer
A498
2.33±0.49 μg/mL
IC50
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP32372
RECORD: Rec_0219051 VERIFIED: YES
Provenance & Taxonomy
Brevibacillus laterosporus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
X(1)=Hmp=2-hydroxy-3-methylpentanoic acid; X(2)=Aba=2-amino-2-butenoic acid; X(4)=Ornithine; X(14)=valinol
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP32372
RECORD: Rec_0227517 VERIFIED: YES
Provenance & Taxonomy
Brevibacillus laterosporus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
X(1)=Hmp=2-hydroxy-3-methylpentanoic acid; X(2)=Aba=2-amino-2-butenoic acid; X(4)=Ornithine; X(14)=valinol
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
Human Intrahepatic Biliary Epithelial Cells (HIBEpiC)
2
IC50
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP32372
RECORD: Rec_0242369 VERIFIED: YES
Provenance & Taxonomy
Brevibacillus laterosporus [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
X(1)=Hmp=2-hydroxy-3-methylpentanoic acid; X(2)=Aba=2-amino-2-butenoic acid; X(4)=Ornithine; X(14)=valinol
Bio-Activity Profile
Antimicrobial Anticancer
PC-3M
6.17±0.24 μg/mL
IC50
Evidence URLhttps://dramp.cpu-bioinfor.org/browse/All_Information.php?dataset=General&id=DRAMP32372
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