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MYP_109741
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Basic Information
Unnamed
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Delivery / Targeting ▸ Barrier transport ▸ Blood-brain barrier shuttle ▸ Blood-Brain Barrier
Delivery / Targeting ▸ Drug delivery vehicle
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Host defense activity
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide signaling
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Neurological / Signaling ▸ Tachykinin peptide
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity
Wound healing/Regeneration ▸ Angiogenesis modulation ▸ Therapeutic angiogenesis
Standard
11 amino acids
C63H97N17O14S
Standard
Sequence
RPKPQQFFGLM
Physicochemical Analysis
1348.61 Da
11.00
1.76
1.55
0.1599
-0.70
0.24
-0.08
47.91
35.45
0.1818
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
510.84
-2.90
16.0
17.0
42.0
95.0
4.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0252102 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Yeast: Candida albicans
0.25 %
MIC
PMID12074933 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12074933/
RECORD: Rec_0278535 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Enterococcus faecalis
0.13 %
MIC
PMID12074933 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12074933/
RECORD: Rec_0281398 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Substance P
9986
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Neuropeptide Neuromodulator Vasoactive Vasodilator Receptor modulation
Experimental: 2.1 (t1/2 of hydrolysis) minutes; /126 seconds; Mammalian: 1 hour; Yeast: 2 min; E. coli: 2 min
PaperSource-linked PubMed record(s) for Substance P (Oryctolagus cuniculus): PMID 8363593##7529108 PMID8363593;7529108 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/8363593/
RECORD: Rec_0291666 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Anticancer
PaperNyeki O., Rill A., Schon I., Orosz A., Schrett J., Bartha L., Nagy J.. Synthesis of peptide and pseudopeptide amides inhibiting the proliferation of small cell and epithelial types of lung carcinoma cells. J. Pept. Sci., 4, 486-495 (1998).
RECORD: Rec_0303706 VERIFIED: YES
Provenance & Taxonomy
Oryctolagus cuniculus [Animal]
Tachykinin
9986
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Tachykinin Neuropeptide Neuromodulator
PMID2478925 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2478925/
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