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MYP_109700
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Basic Information
Crustacean hyperglycemic hormone A
Developmental biology ▸ Molting regulation
Hormonal / Endocrine ▸ Hormone peptide
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Regulatory peptide ▸ Biological regulation
Standard
72 amino acids
C379H581N101O114S7
Standard
Sequence
QVFDQACKGVYDRNLFKKLDRVCEDCYNLYRKPFVATTCRENCYSNWVFRQCLDDLLLSDVIDEYVSNVQMV
Physicochemical Analysis
8600.73 Da
4.85
-2.29
-2.61
-0.0318
-0.29
0.85
-0.09
17.28
82.36
0.1389
12950.00
13325.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
3550.41
-31.56
128.0
119.0
284.0
601.0
12.0
80.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0006207 VERIFIED: YES
Provenance & Taxonomy
Homarus americanus [Animal]
Arthropod CHH/MIH/GIH/VIH hormone
6706
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Pyroglutamate
Amidation
Phe3 D-phenylalanine, in form CHH-A-II
Bio-Activity Profile
Neuropeptide Arthropod neurohormone
PMID2169734 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2169734/
RECORD: Rec_0384896 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide
Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/
RECORD: Rec_0404475 VERIFIED: YES
Provenance & Taxonomy
Homarus americanus [Animal]
Crustacean hyperglycemic hormone
6706
Structure & Mods
disulfide-constrained peptide [Cyclic]
D-residue-containing modified peptide [Mixed]
Pyroglutamate
Amidation
7-43; 23-39; 26-52
3:D-phenylalanine
Bio-Activity Profile
Hormone Endocrine Neuropeptide Neuromodulator Metabolic regulation Physiological regulation Molting regulator
Mammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Crustacean hyperglycemic hormone A (Homarus americanus): PMID 2169734 PMID2169734 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/2169734/