Peptide Database

Peptide NameGlia-gamma1 (p139p153; E140, E148 and E150)

Function Ontology

Immunology ▸ Immunomodulation ▸ Celiac-immunogenic

Standard StatusStandard

Sequence Length15 amino acids

Chemical FormulaC82H118N22O27

DescriptionStandard

        PEQPQQSFPEQERPF
    

Molecular Weight1843.95 Da

Isoelectric Point (pI)4.25

Net Charge (pH 7.0)-2.03

Net Charge (pH 7.4) -2.10

Charge Density (pH 7.0) -0.1355

GRAVY Index-2.04

Hydrophobic Moment 0.44

Boman Index-0.36

Instability Index177.36

Aliphatic Index 0.00

Aromaticity 0.1333

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 796.75

LogP -8.47

H-bond Donors 24.0

H-bond Acceptors 25.0

Rotatable Bonds 56.0

Heavy Atoms 131.0

Ring Count 6.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0060639 VERIFIED: YES

Provenance & Taxonomy

OrganismTriticum aestivum [Plant]

FamilyGliadin

Tax ID4565

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Other ModsDeamidation; Reported substitutions/positions: E140,E148; Reported substitutions/positions: E150

Bio-Activity Profile

Function

Celiac-immunogenic

TargetHuman intestinal T cells / HLA-DQ2

MethodIntestinal T-cell assay