Peptide Database

Peptide NameDefensin 4

Function Ontology

Antimicrobial

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC353H552N98O105S9

DescriptionStandard

        MHKKSVAALSFLFLVLFVTQEIVVTEAKTCEHLADTYRGPCFTNASCDDHCKNKAHLISGTCHNLQCFCTQNC
    

Molecular Weight8137.34 Da

Isoelectric Point (pI)6.92

Net Charge (pH 7.0)-0.14

Net Charge (pH 7.4) -0.74

Charge Density (pH 7.0) -0.0019

GRAVY Index0.08

Hydrophobic Moment 0.55

Boman Index0.08

Instability Index35.72

Aliphatic Index 76.16

Aromaticity 0.0822

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3253.32

LogP -35.07

H-bond Donors 119.0

H-bond Acceptors 119.0

Rotatable Bonds 267.0

Heavy Atoms 565.0

Ring Count 12.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0248079 VERIFIED: NO

Provenance & Taxonomy

OrganismLens ervoides [Bacterium]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antifungal Fungicidal Non-hemolytic Non-ribosomal