Peptide Database

Peptide NameColicin-D

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length717 amino acids

Chemical FormulaC3439H5507N1005O1080S15

DescriptionStandard

        MARYEDTTQFERDVMASMGYAWRGEGWQRGFSDNEDNMLVEAWVGGPPKKPEPLTNVFEKIADINKPISIHPENDDVIPFGDEAKKSYRDDANKAIGLASGITSDLERKMQETDNDIANVSSQLTQPQRTELEKANLNLVLSKLKVKQERLNVLRHNANKSRAHEEYTKYFNEETFMAYDATSWRDNYRKENSKKMTEKRHEEQQHKIDAEAARQRVSVLENEQREKENEVHRLKELEFFAEEARKAEDARKAEEARKAEEARKAEEARKAEEARKAEEARKAEEARKAEEARKAEEARKAEEARKAEEARKAEEARKALFAKAGVLDAPVYTPEKAKAATAALAAAGTMALNRAPGMLQLSTAAEGVLTTTSELAGSIAGAVWRGAIALAEAATVSTAGATVSALVMGFWPTKAGEGSDKLYGRDIVMFGFQANLIAAGKVSISPEMHSVDLPVRGSLVMENGQQQVRLVKTGIGGVPASVSILKAVRDEKTGLDRITLPAVGGAPSRTILVNPAPVGPTAPPHTGNSSPAPVTPVHTGTTVKQADSIVTTSFPADDLKELQDFIYWQPDATGTGVEPIYVMLSSPRDMPGKVSGKGQQVGDGWLNKAGQELGSPVPSQIADKLHGRKFASFDSFRGAFWKAVAADPELSKEFGPDDIERLKLGRAPTVRFKDSAGKRIKYEIHHRDEVAKGGDVYNVDNLNVLTPKRHIEIHKGK
    

Molecular Weight78692.58 Da

Isoelectric Point (pI)6.47

Net Charge (pH 7.0)-3.11

Net Charge (pH 7.4) -4.29

Charge Density (pH 7.0) -0.0043

GRAVY Index-0.65

Hydrophobic Moment 0.65

Boman Index-0.12

Instability Index39.13

Aliphatic Index 71.42

Aromaticity 0.0586

Extinction Coeff. Reduced 68870.00

Extinction Coeff. Oxidized 68870.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0126286 VERIFIED: YES

Provenance & Taxonomy

OrganismSerratia plymuthica [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)