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MYP_109559
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Basic Information
Unnamed
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antiparasitic ▸ Antimalarial
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ Antiprotozoal ▸ Antimalarial ▸ Anti-Plasmodium
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
13 amino acids
C74H130N18O15
Standard
Sequence
ALWKTLLKKVLKA
Physicochemical Analysis
1511.94 Da
10.48
3.79
3.60
0.2917
0.45
0.66
0.10
7.85
157.69
0.0769
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
552.62
-0.28
20.0
19.0
53.0
107.0
2.0
12.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0049413 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes
4.5 μM
Hemolysis
PMID11847217;11937508;16436701;15917541;21741801;16870756 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11847217/
RECORD: Rec_0049854 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 0.0%, E 0.0%, T 61.5%, C 38.5% [Linear]
canonical L-amino-acid peptide [L]
Dodecylamino-succinyl
Amidation
Bio-Activity Profile
Antiparasitic Antimicrobial Antiplasmodial
PaperParaPep: a web resource for experimentally validated antiparasitic peptide sequences and their structures PMID24923818 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24923818/
RECORD: Rec_0053921 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes
80 μM
Hemolysis
PMID11847217;11937508;16436701;15917541;21741801;16870756 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11847217/
RECORD: Rec_0055627 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Dermaseptin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Human erythrocytes
2 μM
Hemolysis
PMID11847217;11937508;16436701;15917541;21741801;16870756 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11847217/
RECORD: Rec_0062314 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Rhodamine conjugation
Amidation
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery Antimicrobial
PMID12119035 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12119035/
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