Peptide Database

Peptide NameT-1-conotoxin Pu5.5

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length18 amino acids

Chemical FormulaC98H124N22O28S4

DescriptionStandard

        ECCPQSPPCCHYYYYGSW
    

Molecular Weight2186.42 Da

Isoelectric Point (pI)5.24

Net Charge (pH 7.0)-1.12

Net Charge (pH 7.4) -1.40

Charge Density (pH 7.0) -0.0622

GRAVY Index-0.73

Hydrophobic Moment 0.16

Boman Index0.08

Instability Index168.96

Aliphatic Index 0.00

Aromaticity 0.2778

Extinction Coeff. Reduced 11460.00

Extinction Coeff. Oxidized 11710.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 777.89

LogP -5.89

H-bond Donors 30.0

H-bond Acceptors 32.0

Rotatable Bonds 56.0

Heavy Atoms 152.0

Ring Count 10.0

Amide Bonds 18.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0021497 VERIFIED: NO

Provenance & Taxonomy

OrganismConus pulicarius [Animal]

FamilyConotoxin

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide2-9; 3-10

Bio-Activity Profile

Function

Toxin

RECORD: Rec_0035527 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Toxic Cytotoxic