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MYP_109519
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Basic Information
Thymopentin
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Immunology ▸ Immune modulation ▸ Immunostimulatory activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
5 amino acids
C30H49N9O9
Standard
Sequence
RKDVY
Physicochemical Analysis
679.76 Da
8.59
0.76
0.55
0.1518
-1.80
0.41
-0.72
-7.08
58.00
0.2000
1490.00
1490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
325.17
-2.19
12.0
10.0
22.0
48.0
1.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0020989 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Immunostimulatory
PaperAudhya T., Scheid M. P., Goldstein G.. Contrasting biological activities of thymopoietin and splenin, two closely related polypeptide products of thymus and spleen. Proc. Natl Acad. Sci. USA, 81, 2847-2849, 1984.
RECORD: Rec_0237274 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic designed peptide
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
Bio-Activity Profile
Antimicrobial Antimycobacterial Immunomodulatory
Mycobacterium smegmatis RIF-susceptible
1000 μg/mL
MIC
PMID24411680 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24411680/
RECORD: Rec_0294014 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Rat erythrocytes
>2000 μg/mL
Hemolysis
PMID24411680 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24411680/
RECORD: Rec_0370874 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic designed peptide
32630
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
None
Amidation
Bio-Activity Profile
Antimicrobial Antimycobacterial Immunomodulatory
Mycobacterium smegmatis RIF-Resistance
2000 μg/mL
IC50
PMID24411680 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24411680/
RECORD: Rec_0382450 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Mycobacterium smegmatis ATCC 14468
1000 μg/mL
MIC
PMID24411680 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24411680/