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MYP_109506
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Basic Information
Brevinin-1pl
Anticancer
Antimicrobial
Standard
24 amino acids
C125H207N29O27S2
Standard
Sequence
FFPIVAGVAAKVLKKIFCTISKKC
Physicochemical Analysis
2612.29 Da
9.90
4.74
4.50
0.1973
1.07
0.68
0.30
17.04
113.75
0.1250
0.00
125.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
894.39
-3.50
33.0
34.0
87.0
183.0
4.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0046943 VERIFIED: YES
Provenance & Taxonomy
Lithobates pipiens [Animal]
Brevinin
8404;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Anticancer
Candida albicans ATCC 10,231
>128 μM
MIC
PaperDiscovery, Development and Optimisation of a Novel Frog Antimicrobial Peptide with Combined Mode of Action Against Drug-resistant Bacteria
RECORD: Rec_0076790 VERIFIED: YES
Provenance & Taxonomy
Lithobates pipiens [Animal]
Brevinin
8404;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Anticancer
E. faecium NCTC 12,697
4 μM
MIC
PaperDiscovery, Development and Optimisation of a Novel Frog Antimicrobial Peptide with Combined Mode of Action Against Drug-resistant Bacteria
RECORD: Rec_0141859 VERIFIED: YES
Provenance & Taxonomy
Lithobates pipiens [Animal]
Brevinin
8404;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Anticancer
MCF-7
7.6 μM
IC50
PaperDiscovery, Development and Optimisation of a Novel Frog Antimicrobial Peptide with Combined Mode of Action Against Drug-resistant Bacteria
RECORD: Rec_0185266 VERIFIED: YES
Provenance & Taxonomy
Lithobates pipiens [Animal]
Brevinin
8404;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Anticancer
HaCaT skin cells
62.71 μM
IC50
PaperDiscovery, Development and Optimisation of a Novel Frog Antimicrobial Peptide with Combined Mode of Action Against Drug-resistant Bacteria
RECORD: Rec_0201369 VERIFIED: YES
Provenance & Taxonomy
Lithobates pipiens [Animal]
Brevinin
8404;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
18-24
Bio-Activity Profile
Antimicrobial Anticancer
Also showed effects on both H838
6.88 μM
IC50
PaperDiscovery, Development and Optimisation of a Novel Frog Antimicrobial Peptide with Combined Mode of Action Against Drug-resistant Bacteria
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