Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC378H628N94O109S8

DescriptionStandard

        MKLLLLFLTVTLLLAQVTPVMKCWGKSGRCRTTCKESEVYYILCKTEAKCCVDPKYVPVKPKLTDTNTSLESTSAV
    

Molecular Weight8490.11 Da

Isoelectric Point (pI)8.99

Net Charge (pH 7.0)4.44

Net Charge (pH 7.4) 4.11

Charge Density (pH 7.0) 0.0585

GRAVY Index0.16

Hydrophobic Moment 0.62

Boman Index0.06

Instability Index16.53

Aliphatic Index 96.05

Aromaticity 0.0658

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3258.55

LogP -28.19

H-bond Donors 121.0

H-bond Acceptors 122.0

Rotatable Bonds 281.0

Heavy Atoms 589.0

Ring Count 10.0

Amide Bonds 77.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0020360 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Animal]

FamilyDefensin

Tax ID9601

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0367805 VERIFIED: NO