Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length472 amino acids

Chemical FormulaC2331H3773N595O664S17

DescriptionStandard

        MFLWCVLVLVSLLSVATGTSAGVKARITQKGLEYGRAIGIESLQQKLRTIQLKDVSGTEKLAIGKVEYSITGMQIVNLGLPKSALRLVPGTGVMLSVGDAYISLRGNWRVKYSWIIKASGSFELAVSELAISTTIAVKSDVTGRPTVSVTKCEATVGSVKVRFHGGASWLYNLFDSFINKDLRNALQKQICPLVTASIAEMNKTLKTLNVLAKVDQYAELEYSMVESPVISNAMIDLGLKGEFFNIGQHEEPPFSPRPFLLPSQDTNMLYIGVSAFSINSAGFVYHRAGALRLYITDGMIPSGSLNRLNTKTFGKFIPQIAKMSPGLMMKLLVETVKEPIITLEPNNMTVQASSKVTAYAIQPNSILSPLFVLKLEASVSAHIYVTGLKLAGHVTLNKIDMSLAESYVGPFQVKSLEDIFTTVVKDVIIPKVNAGVKEGYPLPAIGKMQLVKSQLQVLKDYLLIGTDVKFTG
    

Molecular Weight51302.58 Da

Isoelectric Point (pI)9.39

Net Charge (pH 7.0)12.93

Net Charge (pH 7.4) 12.30

Charge Density (pH 7.0) 0.0274

GRAVY Index0.25

Hydrophobic Moment 0.69

Boman Index0.17

Instability Index30.09

Aliphatic Index 109.00

Aromaticity 0.0763

Extinction Coeff. Reduced 44350.00

Extinction Coeff. Oxidized 44475.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0084256 VERIFIED: NO

Provenance & Taxonomy

OrganismSinocyclocheilus anshuiensis [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria