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MYP_109439
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Basic Information
KFF
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Standard
10 amino acids
C78H104N14O11
Standard
Sequence
KFFKFFKFFK
Physicochemical Analysis
1413.75 Da
10.48
3.76
3.55
0.3756
0.12
0.57
0.11
-36.09
0.00
0.6000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
429.30
2.73
15.0
15.0
47.0
103.0
6.0
9.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0019002 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Listeria monocytogenes J0161
128 μM
MIC
PMID26860980 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26860980/
RECORD: Rec_0042799 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
CPP
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Conjugation with nucleic acid
Nucleic acid is attached via an ethylene glyol linker
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID23305655 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23305655/
RECORD: Rec_0069679 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Listeria monocytogenes ATCC 19111
32 μM
MIC
PMID26860980 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26860980/
RECORD: Rec_0076571 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Listeria monocytogenes F4244
128 μM
MIC
PMID26860980 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26860980/
RECORD: Rec_0148658 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Conjugated LNA with a Cys-succinimidyl trans-4-(maleimidylmethyl)cyclo- hexane-1-carboxylate-C6 (Cys-SMCC-C6) linker
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID25421468 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25421468/
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