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MYP_109433
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Basic Information
Oncocin Onc112 analog b
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
19 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
VXKPPYLPRPRWPRRIYNR
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0055441 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Oncocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
r=D-Arg; X=Orn
Bio-Activity Profile
Antimicrobial Anticancer
HepG2 (10% Cytotoxicity=600 μg/ml)
PMID26334348 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26334348/
RECORD: Rec_0085450 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D amino-acid peptide [Mixed]
Amidation
Ornithine, r: d-arginine at 2; Ornithine, r: d-arginine
Bio-Activity Profile
Antimicrobial Antibacterial
Klebsiella pneumoniae
PMID26334348 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26334348/
RECORD: Rec_0161660 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Oncocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
r=D-Arg; X=Orn
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: SH-SY5Y (<10% Cytotoxicity=600 μg/ml)
PMID26334348 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26334348/
RECORD: Rec_0192588 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Oncocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
r=D-Arg; X=Orn
Bio-Activity Profile
Antimicrobial Anticancer
HeLa (40% Cytotoxicity=601 μg/ml)
PMID26334348 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26334348/
RECORD: Rec_0214944 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Oncocin
32630
Structure & Mods
synthetic linear peptide [Linear]
mixed L/D or modified amino-acid peptide [Mixed]
None
Amidation
r=D-Arg; X=Orn
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID26334348 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26334348/
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