Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC476H772N124O136S10

DescriptionStandard

        MKLFMVLIILLFEVPTDGIRPKKCFNNITGYCRKKCKMGEIYESSCRNGKLCCVDAEENKMFQVVKHPPQPSENSNVSLDYVILPTVTLNTIQI
    

Molecular Weight10728.62 Da

Isoelectric Point (pI)8.56

Net Charge (pH 7.0)2.54

Net Charge (pH 7.4) 2.15

Charge Density (pH 7.0) 0.0270

GRAVY Index-0.06

Hydrophobic Moment 0.58

Boman Index0.04

Instability Index44.66

Aliphatic Index 92.13

Aromaticity 0.0745

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4195.03

LogP -36.22

H-bond Donors 146.0

H-bond Acceptors 150.0

Rotatable Bonds 360.0

Heavy Atoms 746.0

Ring Count 14.0

Amide Bonds 103.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0060804 VERIFIED: NO

Provenance & Taxonomy

OrganismTrichechus manatus latirostris [Bacterium]

FamilyDefensin

Tax ID127582

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence