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MYP_109407
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Basic Information
Decoralin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
11 amino acids
C58H109N15O15
Standard
Sequence
SLLSLIRKLIT
Physicochemical Analysis
1256.58 Da
11.00
1.46
1.25
0.1326
1.23
0.63
0.23
1.37
212.73
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
502.93
-2.72
19.0
17.0
44.0
88.0
0.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0109287 VERIFIED: YES
Provenance & Taxonomy
Oreumenes decoratus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
A.faecalis ATCC 8750
40 μM
MIC
PMID17981364;28105725;28795464 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17981364/
RECORD: Rec_0134117 VERIFIED: YES
Provenance & Taxonomy
Oreumenes decoratus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic
B. thuringiensis (Gram-positive)
PMID17981364;27096870;28267894 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17981364/
RECORD: Rec_0134909 VERIFIED: YES
Provenance & Taxonomy
Oreumenes decoratus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli ATCC 25922
80 μM
MIC
PMID17981364 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17981364/
RECORD: Rec_0141755 VERIFIED: YES
Provenance & Taxonomy
Oreumenes decoratus [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Anticancer Antiparasitic
mouse erythrocytes: not hemo.lytic
0.1-1 μM
HC50
PaperDecoralin, a novel linear cationic alpha-helical peptide from the venom of solitary eumenine wasp Oreumenes decoratus
RECORD: Rec_0146315 VERIFIED: YES
Provenance & Taxonomy
Oreumenes decoratus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Bacillus subtilis CCT 2471
40 μM
MIC
PMID17981364;28105725;28795464 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17981364/
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