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MYP_109407
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Basic Information
Decoralin
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Antimicrobial ▸ Antifungal
Antimicrobial ▸ Antifungal ▸ Anti-Candida
Antiparasitic ▸ Anti-Leishmania ▸ Antileishmanial
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
11 amino acids
C58H109N15O15
Standard
Sequence
SLLSLIRKLIT
Physicochemical Analysis
1256.58 Da
11.00
1.46
1.25
0.1326
1.23
0.63
0.23
1.37
212.73
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
502.93
-2.72
19.0
17.0
44.0
88.0
0.0
10.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0010441 VERIFIED: YES
Provenance & Taxonomy
Oreumenes decoratus [Animal]
Structure & Mods
linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Amidation
Bio-Activity Profile
Antimicrobial Antifungal Anticancer Antiparasitic
A. faecalis ATCC 8750
40 μM
MIC
PaperDecoralin, a novel linear cationic alpha-helical peptide from the venom of solitary eumenine wasp Oreumenes decoratus
RECORD: Rec_0012521 VERIFIED: YES
Provenance & Taxonomy
Oreumenes decoratus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
mouse erythrocytes
1.6 μM
Hemolysis
PMID17981364;28105725;28795464 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17981364/
RECORD: Rec_0039910 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 36.4%, E 0.0%, T 36.4%, C 27.3% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antiparasitic Toxic Antimicrobial Hemolytic Antileishmanial
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0045126 VERIFIED: YES
Provenance & Taxonomy
Oreumenes decoratus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Bacillus subtilis CCT 2471
40 μM
MIC
PMID17981364 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17981364/
RECORD: Rec_0047195 VERIFIED: YES
Provenance & Taxonomy
Oreumenes decoratus [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Candida albicans
6.25 μM
MIC
PMID17981364;28105725;28795464 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/17981364/
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