Peptide Database

Peptide NameGalsulfase

Function Ontology

Therapeutic / Biomedical activity ▸ Enzyme replacement therapy

Standard StatusStandard

Sequence Length255 amino acids

Chemical FormulaC1298H1992N352O371S11

DescriptionStandard

        SGAGASRPPHLVFLLADDLGWNDVGFHGSRIRTPHLDALAAGGVLLDNYYTQPLCTPSRSQLLTGRYQIRTGLQHQIIWPCQPSCVPLDEKLLPQLLKEAGYTTHMVGKWHLGMYRKECLPTRRGFDTYFGYLLGSEDYYSHERCTLIDALNVTRCALDFRDGEEVATGYKNMYSTNIFTKRAIALITNHPPEKPLFLYLALQSVHEPLQVPEEYLKPYDFIQDKNRHHYAGMVSLMDEAVGNVTAALKSSGLWN
    

Molecular Weight28816.55 Da

Isoelectric Point (pI)6.58

Net Charge (pH 7.0)-1.62

Net Charge (pH 7.4) -2.53

Charge Density (pH 7.0) -0.0063

GRAVY Index-0.30

Hydrophobic Moment 0.61

Boman Index0.04

Instability Index45.83

Aliphatic Index 86.08

Aromaticity 0.1059

Extinction Coeff. Reduced 44350.00

Extinction Coeff. Oxidized 44725.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0151541 VERIFIED: YES

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyEnzyme

Tax ID9606

Structure & Mods

Configlinear multidomain protein biologic [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Enzyme replacement

Half-Life9 (6 to 21) minduring the first wk of treatment, 26 (8 to 40) minby the 24th wk..