Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length73 amino acids

Chemical FormulaC374H598N106O97S11

DescriptionStandard

        MILSRKMSCFIFAFLFVLAQFLSGNQLEYSQPLPGVCEPCWLGRGKCRRICTEDEKVVGNCKMNIFCCQRRIR
    

Molecular Weight8484.12 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)5.43

Net Charge (pH 7.4) 5.08

Charge Density (pH 7.0) 0.0744

GRAVY Index0.14

Hydrophobic Moment 0.60

Boman Index0.01

Instability Index69.99

Aliphatic Index 82.74

Aromaticity 0.1096

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3294.83

LogP -27.65

H-bond Donors 123.0

H-bond Acceptors 114.0

Rotatable Bonds 284.0

Heavy Atoms 588.0

Ring Count 12.0

Amide Bonds 79.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0223617 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyDefensin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence