Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC370H594N112O104S9

DescriptionStandard

        MKLLLAFAIISFLAQTTQGSWGAKKCWNNVGRCRGTCRSSEKNHSQCTNKQKCCVKALMIQGIKWWGGQVEDERCP
    

Molecular Weight8563.95 Da

Isoelectric Point (pI)9.46

Net Charge (pH 7.0)7.52

Net Charge (pH 7.4) 7.13

Charge Density (pH 7.0) 0.0989

GRAVY Index-0.40

Hydrophobic Moment 0.70

Boman Index-0.07

Instability Index28.33

Aliphatic Index 64.21

Aromaticity 0.0789

Extinction Coeff. Reduced 22000.00

Extinction Coeff. Oxidized 22375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3546.80

LogP -38.74

H-bond Donors 131.0

H-bond Acceptors 122.0

Rotatable Bonds 292.0

Heavy Atoms 595.0

Ring Count 12.0

Amide Bonds 85.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0137114 VERIFIED: NO

Provenance & Taxonomy

OrganismMonodelphis domestica [Animal]

FamilyDefensin

Tax ID13616

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence