‹ ›
MYP_109359
← PREVIOUS NEXT → BACK
Basic Information
Caerin-1.2 (Frogs, amphibians, animals)
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiviral
Antiviral ▸ Anti-HIV
Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
25 amino acids
C120H200N32O29
Standard
Sequence
GLLGVLGSVAKHVLPHVVPVIAEHL
Physicochemical Analysis
2555.07 Da
7.02
0.02
-0.33
0.0009
1.20
0.43
0.50
29.70
171.20
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
913.73
-3.92
30.0
32.0
79.0
181.0
5.0
24.0
Structural Visualization
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.
2D CHEMICAL STRUCTURE
Drag to move
Drag to move. Use the buttons to zoom.
Experimental Records
RECORD: Rec_0003547 VERIFIED: YES
Provenance & Taxonomy
Litoria caerulea [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral
HIV inhibition of HIV Pseudovirus (PsV) infection in CD4+ T cells
5 μM
IC50
PaperPubMed PMID: 26026377 PMID26026377 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26026377/
RECORD: Rec_0034614 VERIFIED: NO
Provenance & Taxonomy
Litoria caerulea [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0056556 VERIFIED: NO
Provenance & Taxonomy
Ranoidea caerulea [Animal]
Frog skin active peptide (FSAP); Caerin subfamily
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Non-hemolytic
Evidence URLhttps://www.uniprot.org/uniprotkb/P56227/entry
RECORD: Rec_0123413 VERIFIED: YES
Provenance & Taxonomy
Litoria caerulea [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antiviral
PaperPubMed PMID: 26026377 PMID26026377 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26026377/
RECORD: Rec_0138699 VERIFIED: YES
Provenance & Taxonomy
Litoria caerulea [Animal]
Caerin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial
PaperM.A. Apponyi et al. / Peptides 25 (2004) 1035-1054. Host-defence peptides of Australian anurans: structure, mechanism of action and evolutionary significance PMID15203252 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15203252/
1 2 3 NEXT LAST
Showing 5 records on this page · Page 1 of 3