Peptide Database

Peptide NameInsulin-1

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length51 amino acids

Chemical FormulaC254H379N69O72S7

DescriptionStandard

        MAPPQHLCGSHLVDALYLVCGDRGFFYNPKGIVEQCCHRPCDIFDLQSYCN
    

Molecular Weight5775.60 Da

Isoelectric Point (pI)5.73

Net Charge (pH 7.0)-2.29

Net Charge (pH 7.4) -2.76

Charge Density (pH 7.0) -0.0450

GRAVY Index-0.03

Hydrophobic Moment 0.51

Boman Index0.10

Instability Index50.49

Aliphatic Index 74.51

Aromaticity 0.1176

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2222.12

LogP -19.73

H-bond Donors 79.0

H-bond Acceptors 80.0

Rotatable Bonds 179.0

Heavy Atoms 402.0

Ring Count 13.0

Amide Bonds 55.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0346719 VERIFIED: YES

Provenance & Taxonomy

OrganismBatrachoididae [Animal]

FamilyInsulin

Tax ID8065

Structure & Mods

Configlinear peptide with reported disulfide constraint [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide8-37; 20-50; 36-41

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 30 hour; Yeast: >20 hour; E. coli: >10 hour