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MYP_109306
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Basic Information
Pepfect 5
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
not Standard
21 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
AGYLLGXINLKALAALAKKIL
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0088130 VERIFIED: NO
Provenance & Taxonomy
synthetic construct [Synthetic]
PepFect
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Stearylation
Contains X placeholder residue(s)
Bio-Activity Profile
Antimicrobial Anticancer
PaperCell-penetrating peptides, PepFects, show no evidence of toxicity and immunogenicity in vitro and in vivo. PMID21978260 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21978260/ PatentUS20140140929A1
RECORD: Rec_0094336 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Stearylation
Amidation
X=Ornithine
Bio-Activity Profile
Antimicrobial Anticancer
Not available
PMID23357356 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23357356/
RECORD: Rec_0107295 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Stearylation
Amidation
X=Ornithine
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID23357356 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23357356/
RECORD: Rec_0130698 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Stearylation
Amidation
X=Ornithine
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID23357356 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23357356/
RECORD: Rec_0268794 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
NickFect
32630
Structure & Mods
synthetic linear peptide [Linear]
noncanonical stereochemical modification [Modified]
Stearylation
Amidation
O, Ornithine
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID23357356 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23357356/
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