Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length286 amino acids

Chemical FormulaC1446H2280N352O414S10

DescriptionStandard

        MENICEVITSSVSSKLEPYFQTLTMTAKIDNVAGIDYSLLTPPTVTAETLDVQLKGEFFSLAHRSPPPFAPPALAFPTDHDLMVYLGISDYFFNTAGLVYQQSGVLNLTLKDDMIPKESKFRLTTKFFGTLIPQVATMFPDMKVQLLLWVSSPPRLTISPSGLALTPALETQAFAVLPNSSLAPLFLLGMSTNISVEVGTRSNRLVGELSLDKLLLELKHSDIGPFSVELLQTIMNYVVPAAVLPKLNERLQKGIPLPLPDHMQLFNLELQSRQDFLLFGADVHYG
    

Molecular Weight31540.33 Da

Isoelectric Point (pI)5.09

Net Charge (pH 7.0)-8.04

Net Charge (pH 7.4) -8.58

Charge Density (pH 7.0) -0.0281

GRAVY Index0.21

Hydrophobic Moment 0.63

Boman Index0.19

Instability Index40.74

Aliphatic Index 106.68

Aromaticity 0.0874

Extinction Coeff. Reduced 15930.00

Extinction Coeff. Oxidized 15930.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0091212 VERIFIED: NO

Provenance & Taxonomy

OrganismRousettus aegyptiacus (Egyptian rousette) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria