Peptide Database

Peptide NamePreprofallaxidin-2 [Cleaved into: Fallaxidin-3.1; Fallaxidin-3.2]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC444H739N125O140S2

DescriptionStandard

        MASLKKSLFLVLFLGLVSLSICEKEKRENEGNENEEEEENHEEGSEEKRGLLDLAKHVIGIASKLGKRSEEKRGLLDFAKHVIGIASKLGK
    

Molecular Weight10132.50 Da

Isoelectric Point (pI)5.95

Net Charge (pH 7.0)-2.21

Net Charge (pH 7.4) -2.64

Charge Density (pH 7.0) -0.0243

GRAVY Index-0.52

Hydrophobic Moment 0.70

Boman Index-0.10

Instability Index49.56

Aliphatic Index 99.67

Aromaticity 0.0330

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4333.80

LogP -40.55

H-bond Donors 150.0

H-bond Acceptors 143.0

Rotatable Bonds 371.0

Heavy Atoms 711.0

Ring Count 6.0

Amide Bonds 94.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0308276 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria fallax [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetE. cloacae (Gram-negative)

RECORD: Rec_0313253 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria fallax [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetL. innocua (Gram-positive)

RECORD: Rec_0358748 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria fallax [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEnterococcus faecalis (Gram-positive)

RECORD: Rec_0426557 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria fallax [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetMicrococcus luteus (Gram-negative)

FIRST PREV 1 2

Showing 4 records on this page Ã‚Â· Page 2 of 2