Peptide Database

Peptide NamePreprofallaxidin-2 [Cleaved into: Fallaxidin-3.1; Fallaxidin-3.2]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length91 amino acids

Chemical FormulaC444H739N125O140S2

DescriptionStandard

        MASLKKSLFLVLFLGLVSLSICEKEKRENEGNENEEEEENHEEGSEEKRGLLDLAKHVIGIASKLGKRSEEKRGLLDFAKHVIGIASKLGK
    

Molecular Weight10132.50 Da

Isoelectric Point (pI)5.95

Net Charge (pH 7.0)-2.21

Net Charge (pH 7.4) -2.64

Charge Density (pH 7.0) -0.0243

GRAVY Index-0.52

Hydrophobic Moment 0.70

Boman Index-0.10

Instability Index49.56

Aliphatic Index 99.67

Aromaticity 0.0330

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4333.80

LogP -40.55

H-bond Donors 150.0

H-bond Acceptors 143.0

Rotatable Bonds 371.0

Heavy Atoms 711.0

Ring Count 6.0

Amide Bonds 94.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0013165 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria fallax [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0089136 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria fallax [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetL. lactis (Gram-positive)

RECORD: Rec_0210757 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria fallax [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetS. epidermidis (Gram-positive)

RECORD: Rec_0231298 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria fallax [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetS. uberis (Gram-positive)

RECORD: Rec_0266100 VERIFIED: YES

Provenance & Taxonomy

OrganismLitoria fallax [Animal]

FamilyDermaseptin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetB. cereus (Gram-positive)

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