Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC334H523N79O80S8

DescriptionStandard

        MFCYRVIVLALLVVLLLNVALNEAASFPWSCPTLSGVCRKVCLPTELFFGPLGCGKGFLCCVSHFL
    

Molecular Weight7181.73 Da

Isoelectric Point (pI)8.23

Net Charge (pH 7.0)1.52

Net Charge (pH 7.4) 1.14

Charge Density (pH 7.0) 0.0230

GRAVY Index1.24

Hydrophobic Moment 0.49

Boman Index0.42

Instability Index18.52

Aliphatic Index 123.94

Aromaticity 0.1212

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2442.36

LogP -12.58

H-bond Donors 91.0

H-bond Acceptors 91.0

Rotatable Bonds 223.0

Heavy Atoms 501.0

Ring Count 14.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0368368 VERIFIED: NO

Provenance & Taxonomy

OrganismNeolamprologus brichardi [Bacterium]

FamilyDefensin

Tax ID32507

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic

MethodQualitative functional evidence