Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC426H710N142O141S7

DescriptionStandard

        MRTLAILAAILLFALLAQAKSLQERADDAATQEQPGEDDQDLAVSFEENGLSTLRDSGSQARRTCHCRSRCLRRESNSGSCNINGRIFRLCCR
    

Molecular Weight10301.52 Da

Isoelectric Point (pI)7.60

Net Charge (pH 7.0)0.55

Net Charge (pH 7.4) 0.18

Charge Density (pH 7.0) 0.0059

GRAVY Index-0.42

Hydrophobic Moment 0.70

Boman Index-0.19

Instability Index70.17

Aliphatic Index 82.04

Aromaticity 0.0323

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4670.72

LogP -60.82

H-bond Donors 172.0

H-bond Acceptors 150.0

Rotatable Bonds 355.0

Heavy Atoms 716.0

Ring Count 5.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0283848 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca nemestrina [Animal]

FamilyDefensin

Tax ID9545

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence