Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length78 amino acids

Chemical FormulaC387H591N103O101S11

DescriptionStandard

        MKPCPWSRDLFSSCNKRQQFLRPQSVCVCVFAESQAASFPWSCPSLSGVCRKVCLPTELFFGPLGCGKGFLCCVSHFL
    

Molecular Weight8655.18 Da

Isoelectric Point (pI)8.78

Net Charge (pH 7.0)4.49

Net Charge (pH 7.4) 4.07

Charge Density (pH 7.0) 0.0576

GRAVY Index0.28

Hydrophobic Moment 0.53

Boman Index0.13

Instability Index59.45

Aliphatic Index 66.15

Aromaticity 0.1282

Extinction Coeff. Reduced 11000.00

Extinction Coeff. Oxidized 11625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3204.31

LogP -30.79

H-bond Donors 120.0

H-bond Acceptors 118.0

Rotatable Bonds 270.0

Heavy Atoms 602.0

Ring Count 20.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0006091 VERIFIED: YES

Provenance & Taxonomy

OrganismCynoglossus semilaevis [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal