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MYP_109209
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Basic Information
XLAsp-P1
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Standard
5 amino acids
C21H29N5O16
Standard
Sequence
DEDDD
Physicochemical Analysis
607.48 Da
4.05
-5.23
-5.44
-1.0459
-3.50
0.22
-0.87
46.52
0.00
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
366.22
-4.90
11.0
11.0
20.0
42.0
0.0
4.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0166122 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus sciuri
50 μg/mL
MIC
PMID26952034 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26952034/
RECORD: Rec_0181437 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Anticancer Antitumor Cell-growth inhibition
MCF-7 human breast cancer cells
55 %
MTT cell-growth inhibition assay
PaperA novel short anionic antibacterial peptide isolated from the skin of Xenopus laevis with broad antibacterial activity and inhibitory activity against breast cancer cell. Arch Microbiol. 2016;198(5):473-482. DOI:10.1007/s00203-016-1206-8. PMID:26952034. PMID26952034
RECORD: Rec_0191655 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Rothia nasimurium
10 μg/mL
MIC
PMID26952034 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26952034/
RECORD: Rec_0210083 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus ATCC 29213
10 μg/mL
MIC
PMID26952034 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26952034/
RECORD: Rec_0241929 VERIFIED: YES
Provenance & Taxonomy
Xenopus laevis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Rabbit red blood cells
6 %
Hemolysis at 64 μg/mL peptide
PMID26952034 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26952034/
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