Peptide Database

Peptide NameAurein-5.2 (Aurein-5.3)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length71 amino acids

Chemical FormulaC344H568N88O112S3

DescriptionStandard

        MAFLKKSLFLVLFLGLVSLSICEQEKREEENQEEDEENEAASEEKRGLMSSIGKALGGLIVDVLKPKTPAS
    

Molecular Weight7824.91 Da

Isoelectric Point (pI)4.67

Net Charge (pH 7.0)-5.48

Net Charge (pH 7.4) -5.74

Charge Density (pH 7.0) -0.0772

GRAVY Index-0.21

Hydrophobic Moment 0.56

Boman Index0.00

Instability Index60.43

Aliphatic Index 100.28

Aromaticity 0.0423

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3245.08

LogP -29.60

H-bond Donors 110.0

H-bond Acceptors 110.0

Rotatable Bonds 278.0

Heavy Atoms 547.0

Ring Count 5.0

Amide Bonds 74.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0121213 VERIFIED: YES

Provenance & Taxonomy

OrganismRanoidea aurea [Animal]

FamilyFrog skin active peptide (FSAP); Aurein subfamily

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-positive Non-hemolytic

TargetStreptococcus uberis

RECORD: Rec_0165374 VERIFIED: YES