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MYP_109187
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Basic Information
Neutrophil defensin 1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
30 amino acids
C153H227N43O37S6
Standard
Sequence
ACYCRIPACLAGERRYGTCFYLGRVWAFCC
Physicochemical Analysis
3453.09 Da
8.68
2.74
2.45
0.0912
0.48
0.34
0.11
65.10
62.00
0.2000
9970.00
10345.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1280.04
-9.34
54.0
46.0
103.0
239.0
8.0
29.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0295565 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
PaperIsolation, characterization, cDNA cloning, and antimicrobial properties of two distinct subfamilies of alpha-defensins from rhesus macaque leukocytes
RECORD: Rec_0311568 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus and Listeria monocytogenes
PaperPubMed PMID: 10531277 PMID10531277 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10531277/
RECORD: Rec_0380595 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544
Structure & Mods
topology not specified [Not included yet]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Escherichia coli
PaperPubMed PMID: 10531277 PMID10531277 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10531277/
RECORD: Rec_0391710 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0400958 VERIFIED: YES
Provenance & Taxonomy
Macaca mulatta [Animal]
Defensin
9544
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Listeria monocytogenes
PMID10531277 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/10531277/
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