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MYP_109177
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Basic Information
PL-D 44
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
9 amino acids
C66H99N19O11
Standard
Sequence
YRLRVKWKW
Physicochemical Analysis
1334.61 Da
11.10
3.76
3.55
0.4175
-1.32
0.14
-0.45
8.30
75.56
0.3333
12490.00
12490.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
523.77
0.16
21.0
15.0
42.0
96.0
5.0
8.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0274561 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Human acute monocytic leukemia THP-1
191.9 μM
IC50
PMID23478953;28473710 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23478953/
RECORD: Rec_0297518 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
Tumor cells: THP-1
191.9 μM
IC50
PMID23478953 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23478953/
RECORD: Rec_0318776 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Enterococcus faecalis ATCC 29212
50 μg/mL
MIC
PMID23478953;28473710 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23478953/
RECORD: Rec_0329117 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Pseudomonas aeruginosa ATCC 27853
25 μg/mL
MBC
PMID23478953;28473710 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23478953/
RECORD: Rec_0335844 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Mycobacterium tuberculosis lux
3.7 μM
MIC50
PMID23478953;28473710 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23478953/
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