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MYP_109085
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Basic Information
Dermaseptin DPh-1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
25 amino acids
C109H184N30O31
Standard
Sequence
GLWSTIKNVGKEAAIAAGKAALGAL
Physicochemical Analysis
2410.81 Da
9.70
1.76
1.55
0.0704
0.58
0.60
0.31
2.09
117.60
0.0400
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
976.42
-9.19
34.0
33.0
81.0
170.0
2.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0195688 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa hypochondrialis [Animal]
Dermaseptin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Anti-Gram-positive Anti-Gram-negative
Refer PubMed ID 16963159 :- Micrococcus luteus
6.6 μM
MIC
PMID16963159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16963159/
RECORD: Rec_0207455 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa hypochondrialis [Animal]
Dermaseptin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Anti-Gram-positive Anti-Gram-negative
Refer PubMed ID 16963159 :- Micrococcus luteus
6 μM
MIC
PMID16963159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16963159/
RECORD: Rec_0264760 VERIFIED: NO
Provenance & Taxonomy
Phyllomedusa nordestina [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic
RECORD: Rec_0292724 VERIFIED: YES
Provenance & Taxonomy
Phyllomedusa hypochondrialis [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antiprotozoal
Staphylococcus aureus ATCC 6538
6 μM
MIC
PMID16844081;16963159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16844081/
RECORD: Rec_0313479 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial
Human erythrocytes
6 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/16963159/ PMID16963159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16963159/
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