Peptide Database

Peptide NameVGF(375-407)

Function Ontology

Hormonal / Endocrine ▸ Secretory pathway peptide ▸ Secretory granule peptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide precursor

Regulatory peptide ▸ Cell-cell communication

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC138H217N41O64

DescriptionStandard

        GGGEDEVGEEDEEAAEAEAEAEEAERARQNALL
    

Molecular Weight3474.44 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-12.20

Net Charge (pH 7.4) -12.43

Charge Density (pH 7.0) -0.3698

GRAVY Index-1.22

Hydrophobic Moment 0.41

Boman Index-0.22

Instability Index57.18

Aliphatic Index 56.67

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1726.70

LogP -21.66

H-bond Donors 56.0

H-bond Acceptors 52.0

Rotatable Bonds 123.0

Heavy Atoms 243.0

Ring Count 0.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0115484 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyVGF

Tax ID10116

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide precursor Secretory granule peptide

RECORD: Rec_0360702 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0412735 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Cell-Cell Communication