Peptide Database

Peptide NameBig gastrin

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC177H259N45O52S2

DescriptionStandard

        QLHPQDLPHLMTDLSKKKGPWQEEDAAYGWMDF
    

Molecular Weight3913.35 Da

Isoelectric Point (pI)4.86

Net Charge (pH 7.0)-3.06

Net Charge (pH 7.4) -3.38

Charge Density (pH 7.0) -0.0927

GRAVY Index-1.04

Hydrophobic Moment 0.51

Boman Index-0.06

Instability Index49.62

Aliphatic Index 53.33

Aromaticity 0.1212

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1548.91

LogP -10.82

H-bond Donors 50.0

H-bond Acceptors 53.0

Rotatable Bonds 125.0

Heavy Atoms 276.0

Ring Count 11.0

Amide Bonds 35.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0228486 VERIFIED: YES

Provenance & Taxonomy

OrganismMacropus giganteus [Animal]

FamilyBig gastrin

Tax ID9317

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

C-TermAmidation

Other Mods28:Sulfotyrosine

Bio-Activity Profile

Function

Hormone Endocrine Myotropic

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour