Peptide Database

Peptide NameDEFENSIN domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length94 amino acids

Chemical FormulaC450H731N137O148S7

DescriptionStandard

        MRTLAVLAAILLFTLQAQAESLQERADEVATQEQPGEDDQDLAVSFEENGLSTLRDSGSQARRTCYCRNKRCFTPEFDAGKCKVERRTYKLCCR
    

Molecular Weight10652.90 Da

Isoelectric Point (pI)5.46

Net Charge (pH 7.0)-1.53

Net Charge (pH 7.4) -1.86

Charge Density (pH 7.0) -0.0163

GRAVY Index-0.59

Hydrophobic Moment 0.63

Boman Index-0.21

Instability Index57.87

Aliphatic Index 68.62

Aromaticity 0.0638

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4705.65

LogP -55.43

H-bond Donors 171.0

H-bond Acceptors 154.0

Rotatable Bonds 364.0

Heavy Atoms 742.0

Ring Count 8.0

Amide Bonds 102.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0019366 VERIFIED: NO

Provenance & Taxonomy

OrganismMacaca fascicularis [Animal]

FamilyDefensin

Tax ID9541

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Antifungal Fungicide Non-hemolytic

MethodQualitative functional evidence

RECORD: Rec_0135801 VERIFIED: NO