Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length102 amino acids

Chemical FormulaC532H862N156O146S8

DescriptionStandard

        MRLFLMVAILLFQKPTETEQLKKCWGHHIQGNCRKVCRVTEIREVLCENRRYCCLNIKQLEERKKVTVRPRPKPPTFAATFPPYKDVEITPSSGSQDRQYVN
    

Molecular Weight12036.01 Da

Isoelectric Point (pI)9.57

Net Charge (pH 7.0)8.63

Net Charge (pH 7.4) 8.19

Charge Density (pH 7.0) 0.0846

GRAVY Index-0.60

Hydrophobic Moment 0.69

Boman Index-0.18

Instability Index56.08

Aliphatic Index 75.39

Aromaticity 0.0784

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4925.32

LogP -44.83

H-bond Donors 176.0

H-bond Acceptors 165.0

Rotatable Bonds 401.0

Heavy Atoms 842.0

Ring Count 19.0

Amide Bonds 111.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0291510 VERIFIED: NO

Provenance & Taxonomy

OrganismUrocitellus parryii [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence