Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length442 amino acids

Chemical FormulaC2237H3489N593O620S12

DescriptionStandard

        TNPGFVVRITQAGLDYAHQQGITVLEKELAQLRLPDISGDFRIRHVGKVHYEISRLDLRSFHLPHSRISLVPNVGLQVSISNAFAELDGNWRVKLLFIRDHGSFELKAENIYIKINLKLGSDAAGKPTVDTSDCSTRISEVQVHFSGKFGWLYNLFYSAVESRFRKSLESKVCESVARSVHRDLQPYVQTLPVTARIGSMAGIDYSLVAPPAATAQSLDVKLKGEFFSLTHRSPVSFPPPLLALPPAHDRMVYFGASSYFFNTAGFAYQAAGALVFEITDSMIPKDVEFHLNTTTFSAFVPQLEEMYPDMLMKLRLFAPSAPFMNIGPEGVSLRPVVDIQAYAILPDARLAPLFLLSLVSLGTAWLGSSGGALSFPLSAPQVRMLQSIMNVLASSTLLPRLNERLGRGFPLPLPDRIQLYNILLGFHQNFLMLGADVQYQPR
    

Molecular Weight48995.01 Da

Isoelectric Point (pI)8.70

Net Charge (pH 7.0)3.47

Net Charge (pH 7.4) 2.56

Charge Density (pH 7.0) 0.0078

GRAVY Index0.10

Hydrophobic Moment 0.82

Boman Index0.13

Instability Index39.65

Aliphatic Index 99.73

Aromaticity 0.1018

Extinction Coeff. Reduced 37360.00

Extinction Coeff. Oxidized 37485.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0354091 VERIFIED: NO

Provenance & Taxonomy

OrganismRhynochetos jubatus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria