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MYP_108909
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Basic Information
Sub5 (Bac2A variant)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Mycobacterium
Antimicrobial ▸ Antifungal
Standard
12 amino acids
C80H134N30O13
Standard
Sequence
RRWKIVVIRWRR
Physicochemical Analysis
1724.11 Da
12.00
5.76
5.55
0.4799
-0.90
0.43
-0.63
185.95
113.33
0.1667
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
750.52
-2.97
31.0
19.0
57.0
123.0
4.0
11.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0116548 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus epidermidis
0.5 μg/mL
MIC
PMID16041366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16041366/
RECORD: Rec_0116679 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
methicillin-resistant Staphylococcus aureus 43300
2 μM
MIC
PMID30742402 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30742402/
RECORD: Rec_0120447 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic designed peptide
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antimycobacterial Antibacterial Antifungal
Mycobacterium smegmatis mc26
6.2 μM
MIC
PMID23478953 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23478953/
RECORD: Rec_0128318 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae
1.7 μM
MIC
PMID30742402 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30742402/
RECORD: Rec_0140171 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Pseudomonas aeruginosa
2 μg/mL
MIC
PaperHigh-throughput generation of small antibacterial peptides with improved activity. Nat Biotechnol. 2005 Aug;23(8):1008-1012. doi: 10.1038/nbt1113. PMID: 16041366. PMID16041366 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16041366/
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