Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length95 amino acids

Chemical FormulaC493H807N131O133S9

DescriptionStandard

        MGLFMIIAVLLFQKPTVTEQLKKCWDNYVQGRCRKICRVNEVREALCEDGRYCCLNIKELEACKKITKPPRPKPATLALTLPQDYVTIIENFPIL
    

Molecular Weight10986.06 Da

Isoelectric Point (pI)8.90

Net Charge (pH 7.0)4.44

Net Charge (pH 7.4) 4.09

Charge Density (pH 7.0) 0.0468

GRAVY Index-0.05

Hydrophobic Moment 0.70

Boman Index-0.00

Instability Index39.68

Aliphatic Index 101.58

Aromaticity 0.0737

Extinction Coeff. Reduced 9970.00

Extinction Coeff. Oxidized 10345.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4258.35

LogP -30.30

H-bond Donors 151.0

H-bond Acceptors 147.0

Rotatable Bonds 366.0

Heavy Atoms 766.0

Ring Count 15.0

Amide Bonds 102.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0281247 VERIFIED: NO

Provenance & Taxonomy

OrganismHylobates lar [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence