Peptide Database

Peptide NameSLAY-screened peptide P155

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length13 amino acids

Chemical FormulaC55H95N15O19S2

DescriptionStandard

        AMQIPNSLCAISS
    

Molecular Weight1334.56 Da

Isoelectric Point (pI)5.56

Net Charge (pH 7.0)-0.21

Net Charge (pH 7.4) -0.42

Charge Density (pH 7.0) -0.0165

GRAVY Index0.75

Hydrophobic Moment 0.37

Boman Index0.30

Instability Index16.03

Aliphatic Index 105.38

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 550.60

LogP -7.30

H-bond Donors 19.0

H-bond Acceptors 21.0

Rotatable Bonds 42.0

Heavy Atoms 91.0

Ring Count 1.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0392888 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/