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MYP_108787
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Basic Information
Eumenitin (Er-12; Insects, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
15 amino acids
C78H137N19O19
Standard
Sequence
LNLKGIFKKVASLLT
Physicochemical Analysis
1645.04 Da
10.30
2.76
2.55
0.1838
0.76
0.58
0.23
-23.33
156.00
0.0667
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
632.33
-3.40
22.0
22.0
58.0
116.0
1.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0004742 VERIFIED: YES
Provenance & Taxonomy
Eumenes rubronotatus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus saprophytius (CS)
6 μM
MIC
PMID16762455;18206199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16762455/
RECORD: Rec_0024347 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0070977 VERIFIED: YES
Provenance & Taxonomy
Eumenes rubronotatus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
6 μM
MIC
PMID16762455;18206199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16762455/
RECORD: Rec_0074243 VERIFIED: YES
Provenance & Taxonomy
Eumenes rubronotatus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
E-cloacae ATCC 23355
>60 μM
MIC
PaperEumenitin, a novel antimicrobial peptide from the venom of the solitary eumenine wasp Eumenes rubronotatus.
RECORD: Rec_0088305 VERIFIED: YES
Provenance & Taxonomy
Eumenes rubronotatus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa ATCC 15442
30 μM
MIC
PMID16762455;18206199 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/16762455/
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